Growth Hormone Peptides Enfuvirtide / T-20 For HIV Aids CAS
Enfuvirtide Acetate (T-20)
Enfuvirtide Sequence :
Enfuvirtide No. : 159519-65-0
Enfuvirtide Molecular Formula : C204H301N51O64
Enfuvirtide Molecular Weight :4492
Enfuvirtide Purity (HPLC): 98.0%min.
Enfuvirtide Apearance : White to off-white amorphous solid
Enfuvirtide Single Impurity (HPLC) : 0.5%max
Enfuvirtide Amino Acid Composition : 10% of theoretical
Enfuvirtide Peptide Content (N%): 80.0%
Enfuvirtide Water Content (Karl Fischer) : 8.0%
Enfuvirtide TrifluoroAcetate Content(HPIC): 12.0%
Enfuvirtide MS (ESI): Consistent
Enfuvirtide Mass Balance : 95.0~105.0%
Enfuvirtide Delivery: Express courier.
1 AppearanceWhite or slightly yellowish powderWhite powder
2 SolubilitySoluble in water or 1% acetic acid at a concentration
of 1mg/ml to give a clear, colorless solutionConforms
3 Identity by HPLCThe retention is same with the reference
4 Specific Optical Rotation-65.0- -75.0° (c=0.5, 95%HAc)-71.3°
5 Amino Acid Composition± 10% of theoreticalConforms
6 Peptide Purity (By HPLC)≥ 98.0% by area integration98.8%
7 Related Substance (By HPLC)Total Impurities(%) ≤ 2.0% Largest
Single Impurity (%) ≤ 1.0%1.2% 0.7%
8 Acetate Content≤ 15.0%13.8%
9 Water Content (Karl Fischer) ≤ 5.0%1.5%
|Product Name||Enfuvirtide (T-20)|
|Appearance||White to off-white amorphous solid|
|Single Impurity (HPLC)||0.5%max|
|Amino Acid Composition||¡À10% of theoretical|
|Peptide Content (N%)||¡Ý80.0%|
|Water Content (Karl Fischer)||¡Ü8.0%|
Why is this medication prescribed?
Enfuvirtide is used along with other medications to treat human
immunodeficiency virus (HIV) infection. Enfuvirtide is in a class
of medications called HIV entry and fusion inhibitors. It works by
decreasing the amount of HIV in the blood. Although enfuvirtide
does not cure HIV, it may decrease your chance of developing
acquired immunodeficiency syndrome (AIDS) and HIV-related illnesses
such as serious infections or cancer. Taking these medications
along with practicing safer sex and making other life-style changes
may decrease the risk of transmitting (spreading) the HIV virus to
How should this medicine be used?
Enfuvirtide comes as a powder to be mixed with sterile water and
injected subcutaneously (under the skin). It is usually injected
twice a day. To help you remember to inject enfuvirtide, inject it
at about the same times each day. Follow the directions on your
prescription label carefully, and ask your doctor or pharmacist to
explain any part you do not understand. Use enfuvirtide exactly as
directed. Do not use more or less of it or use it more often than
prescribed by your doctor.
Enfuvirtide controls HIV but does not cure it. Continue to use
enfuvirtide even if you feel well. Do not stop using enfuvirtide
without talking to your doctor. If you miss doses or stop using
enfuvirtide, your condition may become more difficult to treat.When
your supply of enfuvirtide starts to run low, get more from your
doctor or pharmacist.
You will receive your first dose of enfuvirtide in your doctor's
office. After that, you can inject enfuvirtide yourself or have a
friend or relative perform the injections. Your doctor will train
the person who will be injecting the medication, and will test him
to be sure he can give the injection correctly. Be sure that you
and the person who will be giving the injections read the
manufacturer's information for the patient that comes with
enfuvirtide before you use it for the first time at home.
You can inject enfuvirtide anywhere on the front of your thighs,
your stomach, or upper arms. Do not inject enfuvirtide in or near
your navel (belly button) or in any area directly under a belt or
waistband; near the elbow, knee, groin, the lower or inner
buttocks; or directly over a blood vessel. To reduce the chances of
soreness, choose a different area for each injection. Keep track of
the areas where you inject enfuvirtide, and do not give an
injection into the same area two times in a row. Use your
fingertips to check your chosen area for hard bumps under the skin.
Never inject enfuvirtide into any skin that has a tattoo, scar,
bruise, mole, a burn site, or has had a reaction to a previous
injection of enfuvirtide.
Never reuse needles, syringes, vials of enfuvirtide, or vials of
sterile water. Dispose of used needles and syringes in a
puncture-resistant container. Do not put them in a trash can. You
can dispose of used alcohol pads and vials in the trash, but if you
see blood on an alcohol pad, put it in the puncture-resistant
container. Talk to your doctor or pharmacist about how to dispose
of the puncture-resistant container.
Before preparing an enfuvirtide dose, wash your hands with soap and
water. After you wash your hands, do not touch anything except the
medication, supplies, and the area where you will inject the
Ask your pharmacist or doctor for a copy of the manufacturer's
injection information for the patient. Carefully read the
manufacturer's instructions to learn how to prepare and inject your
dose. Ask your doctor or pharmacist if you have questions about how
to inject enfuvirtide.
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