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CAS 147118 35 2 J6 METHYL 3R BUTYLDIMETHYLSIL6 Triphenylphosphoranylidenehexanoate

Categories Rosuvastatin Intermediates
Certification: cGMP standard
Place of Origin: China
MOQ: 1kg
Packaging Details: Drums
Name: Rosuvastatin Intermediate
CAS: 147118-35-2
Code: J6
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    CAS 147118 35 2 J6 METHYL 3R BUTYLDIMETHYLSIL6 Triphenylphosphoranylidenehexanoate

    CAS : 147118-35-2 J6 METHYL ( 3R ) - ( TERT - BUTYLDIMETHYLSILYLOXY ) - 5 - OXO - 6 -TRIPHENYLPHOSPHORANYLIDENEHEXANOATE Rosuvastatin Intermediate


    Competitive Advantage:

    Produced under cGMP conditions, support customers’ registrations, Approved by many esteemed companies


    Description:

    Rosuvastatin Calcium is the active ingredient (API) of branded drug Crestor. It was innovated by the Japanese drug maker Shionogi and cooperated the marketing with AstraZeneca. Rosuvastatin Calcium is the new generation of statins drugs after Lovastatin, Simvastatin and Atorvastatin. It is a fully synthesized product and used to treat high cholesterol and to prevent cardiovascular disease. Some persons also call it super statin to express its good effect. The annual sales of Crestor exceed US dollars 6.6 Billion in 2014. The first generic version of Crestor will launch in US in 2016.

    ( 3R ) - (Tert - butyldimethylsilyloxy ) - 5 - oxo - 6 - triphenylphosphoranlyidenehexanoate CAS No. : 147118-35-2 is one of its intermediates. There are several synthesis routes to manufacture this intermediate but some routes are protected by the patents in some countries including Europe, USA and China. We strictly obey the laws and our commercial products are manufactured without infringing such patents. But anyway, the buyers should know the patent status by themselves. We promise to supply the real route of synthesis to the buyers. The buyers should take the risks of patent infringement by themselves.


    Chemical Name

    ( 3R ) - (Tert - butyldimethylsilyloxy ) - 5 - oxo - 6 - triphenylphosphoranlyidenehexanoate

    SHORT CodeJ6
    CAS No.

    147118-35-2

    Molecular FormulaC31H39O4PSi
    Molecular Weight

    534.70

    UsageRosuvastatin intermediate
    ApperanceWhite to off-white powder
    Melting Point

    77.5 - 78.5 Deg C

    Purity98.0 % min


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